Vinyl Chloride And Brain Cancer

Others are used in manufacturing to make the things we use every day like certain plastics.
Vinyl chloride and brain cancer. Iarc monographs on the evaluation of carcinogenic risks to humans vol 97. Which cancers are associated with exposure to vinyl chloride. The issue is the strength of the association between vinyl chloride an ingredient in polyvinyl chloride pvc plastic and a byproduct of some chemical processes and brain cancer. It is believed that vinyl chloride found its way from the plant to the wells where the residents get their water.
This is the largest non occupational brain cancer cluster ever identified. Vinyl chloride is an organochloride with the formula h 2 c chcl that is also called vinyl chloride monomer vcm or chloroethene this colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride pvc. This toxic chemical is a known human carcinogen causing liver cancer brain cancer and some cancers of the blood. Other cancers potentially associated with vinyl chloride exposure are nervous system cancers including brain cancer lymphoma leukemia and soft tissue cancers.
Bofetta p matisane l mundt ka dell ld. Manufacturers use vinyl chloride to produce polyvinyl chloride or pvc. 1 3 butadiene ethylene oxide and vinyl halides vinyl fluoride vinyl chloride and vinyl bromide. Meta analysis of studies of occupational exposure to vinyl chloride in relation to cancer mortality.
Some glioblastoma multiforme patients develop the brain tumor after exposure to certain substances. About 13 billion kilograms are produced annually. It has also been liked to brain and lung tumors and malignant haematopoietic lymphatic tumors. One man from a plant in louisville kentucky developed angiosarcoma a rare cancer in his liver.
Vinyl chloride has been found in the air near vinyl chloride manufacturing and processing plants hazardous waste sites and landfills. Vinyl chloride has also been associated with mammary breast cancer. Because the community is isolated the common factor that seems to be causing the cancer is a vinyl food wrap factory near the town. Vinyl chloride also causes cancer in laboratory animals following lifetime inhalation or oral exposure predominately in the liver.
Vinyl chloride exposure is associated with an increased risk of a rare form of liver cancer hepatic angiosarcoma as well as brain and lung cancers lymphoma and leukemia. How can exposures be reduced.